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Configure Claude Code for Hours‑Long Autonomy

  • Claude Opus 4.5 can stay autonomous for about 4 hours 49 minutes at a 50 % completion rate, a dramatic leap from earlier models like GPT‑4, which only lasted roughly 5 minutes.
  • To achieve multi‑hour runs you must configure the Claude Code “agent harness” for added persistence; simply invoking Claude in the CLI won’t keep it alive.